I saw my neurologist (Dr. AbdelRazek) today for my semi-annual checkup, and one of the things we discussed was vaccines. He thinks I should get most vaccines, because T cells exist, but doesn't think I should bother with the flu vaccine, because that one isn't very effective in people who aren't taking medication that knocks out their B cells. I didn't ask about the omicron booster specifically, because I didn't think of it: I was asking about a second dose of Evusheld, and whether there's an MS medication that is as effective as the one I'm on now, and doesn't interfere with vaccines. [There is one, Tysabri, which I have already taken as many doses of as I can safely have in my lifetime.]

I told him I'd been tested for anti-covid T cells, and the test found that I do have some, and he was surprised and interested, because he hadn't heard about that test. I used MyChart to send him a link to the faq page for that test, and he thanked me.

He is going to look into a second dose of Evusheld; as far as he knows, the FDA emergency use authorization for that is for only one dose per patient.

I asked the doctor to write a new gabapentin prescription, for the dose I'm actually taking; he did, and Capsule will be delivering it this evening. I told him that yes, at that dosage it works very well, meaning I only have leg spasms occasionally and they are much milder than at the lower dosage.

He says I am clinically stable, based partly on the low-tech neurology, things like moving pegs in and out of slots, walking 25 feet, and having a light shined in my eyes, and partly on my answers to his questions. He is putting in an order for an MRI, head only, no contrast; Mt. Auburn radiology will contact me to schedule that, and if I don't hear from him within a week after the MRI, that means it's good news. My next MRI will be head, cervical spine, and thoracic spine, probably with contrast.

He think my previous doctor's diagnosis of pseudo-bulbar affect was correct, even though I didn't respond to the drug that's commonly used for that (Nudexa). He said the mechanism of action of mirtazapine, the antidepressant Dr. Segal prescribed along with the bubropion, is similar to Nudexa's. This doesn't seem to have any clinical relevance--the treatment I'm on is working pretty well--but I'm noting it here anyway.

[as usual, this is partly for my later reference]
I saw Dr. Segal this morning, and told her that yes, I want to add a second antidepressant. She couldn't remember, and hadn't written down, which atypical antidepressant she had been thinking of the last time I saw her, so we discussed options starting with what I'm on now (welbutrin). After considering which antidepressants I've tried before, and likeliest side effects of the different drugs we were considering, we settled on mirtazepine, to be taken late in the day because one of the commonest side effects is sedation. ("Side effect" is an interesting term; the pharmacist asked if I was taking it for sleep.)

I asked if I can add that to the evening meds I currently take around 9-9:30 p.m., and she said yes. One dose a day, starting at 7.5 mg (half a pill) to be increased to 15 mg in a week or so if I don't have bad side effects other than sedation. Oddly (not my adjective) it is more sedating at the lower dose, so if the only problem is excess sleepiness, increasing to 15 mg could fix that. Dr. Segal also said that if it's helping, but not enough, the dose can be increased up to 45 mg/day.

Dr. Segal recommended this in part because it may help with my sleep, though I noted that part of why I'm not sleeping well is the tennis elbow, which is still at the point where my wrist hurts every time I wake up, making it harder, and less appealing, to go back to sleep.

I also filled the prescription for the diclofenac (NSAID) gel; twice a day, but I'm waiting until evening for the first dose because I had naproxen this morning.
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